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Cells build and break large biological molecules using two opposite chemical processes: dehydration synthesis and hydrolysis. Dehydration synthesis joins small units called monomers into larger polymers by removing a water molecule. Hydrolysis breaks polymers into monomers by adding water.

These reactions matter because they help cells store energy, build structures, digest food, and recycle molecules.

Key Facts

  • Dehydration synthesis joins monomers: monomer + monomer -> polymer segment + H2O.
  • Hydrolysis breaks bonds using water: polymer segment + H2O -> monomer + monomer.
  • In dehydration synthesis, one monomer often loses H and another loses OH, forming H2O.
  • In hydrolysis, H from water attaches to one product and OH attaches to the other product.
  • Proteins form by dehydration synthesis of amino acids, creating peptide bonds.
  • Polysaccharides such as starch form from monosaccharides and can be hydrolyzed back into sugars.

Vocabulary

Monomer
A small molecular building block that can bond with other similar units to form a polymer.
Polymer
A large molecule made of many repeating monomer units bonded together.
Dehydration synthesis
A reaction that joins molecules by removing the atoms needed to form water.
Hydrolysis
A reaction that breaks a chemical bond by adding water across the bond.
Peptide bond
A covalent bond that links amino acids together in proteins.

Common Mistakes to Avoid

  • Thinking dehydration synthesis adds water, which is wrong because it removes H and OH from reactants to produce H2O while forming a new bond.
  • Thinking hydrolysis builds polymers, which is wrong because hydrolysis uses water to break bonds and separate monomers or smaller units.
  • Forgetting to count water molecules, which is wrong because each bond formed by dehydration synthesis usually releases one H2O and each bond broken by hydrolysis usually uses one H2O.
  • Assuming all biomolecules use the same bond name, which is wrong because carbohydrates, proteins, lipids, and nucleic acids have different linkage types.

Practice Questions

  1. 1 A cell joins 8 glucose monomers into one polysaccharide chain using dehydration synthesis. How many water molecules are released?
  2. 2 A protein fragment contains 12 amino acids in a single chain. How many peptide bonds must be hydrolyzed to break it completely into individual amino acids, and how many water molecules are used?
  3. 3 Explain why dehydration synthesis and hydrolysis are considered opposite processes, using the role of water and chemical bonds in your answer.