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Biology Grade 9-12

Biology: Homeostasis Case Studies: Temperature, Glucose, and Water

Analyzing feedback loops that keep internal conditions stable

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Practice applying homeostasis concepts to body temperature, blood glucose, and water balance case studies.

Read each case study carefully. Identify the variable being regulated, the sensors, control center, effectors, and feedback involved. Show your reasoning in the space provided.

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Analyzing feedback loops that keep internal conditions stable

Biology - Grade 9-12

Instructions: Read each case study carefully. Identify the variable being regulated, the sensors, control center, effectors, and feedback involved. Show your reasoning in the space provided.
  1. 1
    Human body sweating with widened skin blood vessels releasing heat.

    A student runs outside on a hot day. Their body temperature rises from 37.0°C to 38.2°C. They begin sweating and blood vessels near the skin widen. Identify the regulated variable, the response, and whether this is negative or positive feedback.

  2. 2

    After sitting in a cold classroom, a student begins to shiver and their skin feels cool. Explain how shivering helps maintain homeostasis.

  3. 3
    Unlabeled fever curve rising above normal and returning to baseline with a temporary raised set point.

    A graph shows body temperature increasing from 37°C to 39°C during a fever, then returning to 37°C after several hours. Describe what is happening to the set point during a fever and how that affects body responses.

  4. 4
    Insulin released by the pancreas helps glucose move from blood into cells and the liver.

    A person eats a meal high in carbohydrates. Their blood glucose level rises. Explain the role of insulin in restoring homeostasis.

  5. 5
    Glucagon signals the liver to release glucose into the blood.

    A person has not eaten for many hours, and their blood glucose level drops. Explain the role of glucagon in restoring homeostasis.

  6. 6
    Without enough insulin, glucose remains high in the blood and little enters cells.

    A patient has type 1 diabetes, in which the pancreas produces little or no insulin. After eating a high-carbohydrate meal without taking insulin, predict what will happen to the patient's blood glucose and explain why.

  7. 7
    Circular feedback loop showing insulin lowering high blood glucose after a meal.

    Complete the feedback pathway: Blood glucose rises after a meal. The pancreas detects the change. The pancreas releases insulin. Body cells take in glucose and the liver stores glucose. What happens next, and why is this negative feedback?

  8. 8
    Kidneys respond to excess water by producing a larger volume of dilute urine.

    A student drinks a large bottle of water quickly. Their blood becomes slightly more dilute. Predict how the kidneys help restore water balance.

  9. 9
    ADH signals the kidneys to reabsorb water after sweating, producing less concentrated urine.

    A person exercises for an hour and sweats heavily but does not drink water. Their blood becomes more concentrated. Explain how the hormone ADH helps maintain homeostasis.

  10. 10
    Dark low-volume urine with water reabsorption suggests dehydration and high ADH.

    A urine sample is very dark yellow and low in volume. Based on homeostasis, what might this indicate about the person's hydration status and ADH level?

  11. 11

    Compare temperature regulation and blood glucose regulation. Name one similarity and one difference between the two homeostatic systems.

  12. 12
    Runner showing homeostatic responses for heat, low glucose, and water loss.

    A runner finishes a race. Their body temperature is high, blood glucose is lower than before the race, and they have lost water through sweat. Identify one homeostatic response for each variable.

  13. 13
    Feedback pathway for low body temperature from cold stimulus to shivering response.

    The diagram shows a feedback loop with these steps: stimulus, receptor, control center, effector, response. Use the example of low body temperature to fill in each step.

  14. 14
    Excess blood glucose overwhelms kidney reabsorption and glucose appears in urine.

    A person with untreated diabetes may have glucose in their urine. Explain why glucose might appear in urine when blood glucose is extremely high.

  15. 15
    Desert hiker showing heat regulation and water conservation responses.

    Analyze this case: A hiker is lost in a dry desert for several hours. They are hot, thirsty, sweating less than before, and producing very little urine. Explain how at least two homeostatic systems are responding and why these responses matter.

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