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This AP Biology reference sheet brings together the equations and concepts students use most often when solving data-based biology problems. It supports quick review for labs, free-response questions, and multiple-choice practice. Students need it because AP Biology often tests whether they can choose the correct model, substitute values correctly, and explain biological meaning from a calculation.

Key Facts

  • Mean is calculated as x-bar = sum of all values / n, where n is the number of data points.
  • Standard deviation measures spread around the mean and is commonly used to compare variation among biological samples.
  • Chi-square is calculated as X2 = sum of (observed - expected)^2 / expected, and a larger value means a larger difference between observed and expected results.
  • Hardy-Weinberg allele frequencies follow p + q = 1, and genotype frequencies follow p^2 + 2pq + q^2 = 1.
  • Population growth can be modeled as dN/dt = rN for exponential growth, where N is population size and r is the per capita growth rate.
  • Logistic growth can be modeled as dN/dt = rN((K - N) / K), where K is carrying capacity.
  • Water potential is calculated as psi = psi_s + psi_p, where psi_s is solute potential and psi_p is pressure potential.
  • Free energy change is calculated as delta G = delta H - T delta S, and a negative delta G indicates an energetically favorable process.

Vocabulary

Chi-square test
A statistical test used to compare observed data with expected data and decide whether differences are likely due to chance.
Hardy-Weinberg equilibrium
A model describing a population in which allele and genotype frequencies stay constant across generations when no evolutionary forces act.
Carrying capacity
The maximum population size an environment can support with its available resources.
Water potential
A measure of the tendency of water to move from one area to another, usually from higher potential to lower potential.
Free energy
The usable energy in a system that can do work during a biological or chemical process.
Allele frequency
The proportion of a specific allele among all alleles for a gene in a population.

Common Mistakes to Avoid

  • Using genotype frequency as allele frequency is wrong because p and q represent alleles, not whole genotypes.
  • Forgetting to square the difference in a chi-square calculation is wrong because X2 requires (observed - expected)^2 for each category.
  • Treating standard deviation as standard error is wrong because standard deviation describes variation in data, while standard error estimates uncertainty in the sample mean.
  • Ignoring units in water potential problems is wrong because pressure potential and solute potential must use the same units before they are added.
  • Assuming exponential growth continues forever is wrong because real populations often face limited resources and may shift toward logistic growth.

Practice Questions

  1. 1 In a population at Hardy-Weinberg equilibrium, the frequency of the recessive phenotype is 0.16. Find q, p, and the heterozygote frequency 2pq.
  2. 2 A chi-square test has observed counts of 42 and 58, while expected counts are 50 and 50. Calculate X2.
  3. 3 A population has N = 500 and r = 0.04. Using exponential growth, calculate dN/dt = rN.
  4. 4 Explain why a population that is not evolving must meet multiple Hardy-Weinberg conditions, including random mating and no natural selection.