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Diffusion & Osmosis Lab

Explore how particles move across a semipermeable membrane driven by concentration gradients. Adjust concentrations on each side, set membrane permeability, and watch diffusion drive the system toward equilibrium through Fick's First Law.

Guided Experiment: Observing Diffusion Across a Membrane

If you create a large concentration difference between left and right sides, what do you predict will happen to particle movement over time?

Write your hypothesis in the Lab Report panel, then click Next.

Controls

Left Concentration2.00 mol/L
Right Concentration0.50 mol/L
Temperature298.00 K
Diffusion Coefficient (D)1.00 ×10⁻⁹ m²/s
Membrane Permeability0.80

Results

J=DΔcΔx=1.5000 mol/(m2\cdotps)J = -D \cdot \frac{\Delta c}{\Delta x} = 1.5000 \text{ mol/(m}^2 \text{·s)}
Concentration Gradient
1.500 mol/L
Diffusion Flux
1.5000 mol/(m²·s)
Osmotic Pressure (Left)
48.908 atm
Osmotic Pressure (Right)
12.227 atm
Net Osmotic Pressure
36.681 atm
Solution Classification
Hypertonic (outside > inside)

Concentration vs Time

Left sideRight side

Press Run to simulate concentration equilibration over time.

Data Table

(0 rows)
#TrialTime(s)Conc Left(mol/L)Conc Right(mol/L)Gradient(mol/L)Flux(mol/(m²·s))
0 / 500
0 / 500
0 / 500

Reference Guide

Diffusion

Diffusion is the net movement of particles from a region of high concentration to a region of low concentration. It requires no energy and continues until equilibrium is reached.

The driving force is the concentration gradient — the steeper the gradient, the faster the net diffusion. At equilibrium, particles still move, but with no net flow in either direction.

Fick's First Law

Fick's First Law relates diffusion flux to the concentration gradient.

J=DdcdxJ = -D \frac{dc}{dx}

Where J is flux (mol/m²·s), D is the diffusion coefficient (m²/s), and dc/dx is the concentration gradient. The negative sign means flux flows from high to low concentration.

Osmosis

Osmosis is the movement of solvent (water) molecules through a semipermeable membrane from a region of low solute concentration to high solute concentration.

The membrane allows small solvent molecules to pass but blocks larger solute molecules. Water moves to dilute the more concentrated solution, generating osmotic pressure.

Osmotic Pressure

The Van't Hoff equation gives the osmotic pressure of a dilute solution.

π=MRT\pi = MRT

Where π is osmotic pressure (atm), M is molarity (mol/L), R is 0.08206 L·atm/(mol·K), and T is temperature in Kelvin. Higher concentration or higher temperature means greater osmotic pressure.